Lancet Commission - After asthma: redefining airways diseases

Professors Ian Pavord and Andy Bush
14 Sep 2017

Professors Ian Pavord and Andy Bush of the Asthma UK Centre for Applied Research have co-chaired a new Lancet Commission on asthma, published this week - working with several other members of the Centre.

Discussing the importance of the Lancet Commission to the work of the Asthma UK Centre for Applied Research, they said

Personalising asthma treatment is pivotal to the Asthma UK Centre for Applied Research. The Commission advocates moving from the umbrella diagnosis 'asthma' to determining the treatable components of the airway disease. We want patients to be asking 'What sort of asthma do I have' and getting treatment depending  on the answer to that question, rather than the current 'one size fits all' approach.

Andy Bush - profiled - available on The Lancet website

Ian Pavord - profiled - available on The Lancet website

The Lancet Commission

Executive Summary

Progress in reducing hospital admissions and mortality in people with asthma have stalled in the past 10 years. This Lancet Commission examines where we are in the understanding of this heterogeneous syndrome and where we need to go to kickstart a new era of examining, monitoring, treating, and ultimately preventing airways diseases. The Commissioners recommend to deconstruct airway disease into component parts before planning treatment with a focus on traits that are identifiable and treatable. This approach will require a complete change in how we think about airways diseases with the goal of achieving real precision treatment with better patient outcomes. In addition, primary prevention and disease-modifying interventions need to become a more important ambition. It is unacceptable that people still die from asthma attacks in 2017.

After asthma: redefining airways diseases

Ian D Pavord, Richard Beasley, Alvar Agusti, Gary P Anderson, Elisabeth Bel, Guy Brusselle, Paul Cullinan, Adnan Custovic, Francine M Ducharme, John V Fahy, Urs Frey, Peter Gibson, Liam G Heaney, Patrick G Holt, Marc Humbert, Clare M Lloyd, Guy Marks, Fernando D Martinez, Peter D Sly, Erika von Mutius, Sally Wenzel, Heather J Zar, Andy Bush

The Lancet.   Published: September 11, 2017

Read the full commission, and listen to Professors Ian Pavord and Andy Bush discuss the work, on The Lancet website

© 2015 AUKCAR